The weight of being a Hollywood star can take a toll on a person’s weight.
In an industry obsessed with physical appearance, a few extra pounds on the hip or a suddenly pronounced jawline instantly becomes the subject of a headline. Ozempic has only been fuel for more and more of those conversations.
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Opinion of Dr. Sarah Meehan O’Callghan
Ozempic is the new wonder drug, according to some of the latest news headlines. So it is no wonder in a celebrity culture obsessed with weight and size, that a drug that purports to induce weight loss would become the talk of the town.
We need to remember that while Ozympic has been designed to treat obesity, it can also be a substance of abuse for people who are preoccupied with being thin.
Another point to remember is that while the drug treats obesity, obesity and general disordered issues with food are often related to underlying emotional issues (see the extensive work on this issue by psychotherapist Susie Orbach). These issues do not just magically disappear by taking a drug. – Dr. Sarah Meehan O’Callghan
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A number of celebrities have recently shared their experiences with taking Ozempic injections—or other GLP-1 medication such as Mounjaro or Wegovy—normally prescribed to maintain healthy blood sugar levels but now infamous for its weight loss effects.
Here are some stars who have admitted to taking the medication for weight loss and others who have vehemently denied taking it.
Kelly Osbourne
Kelly Osbourne has denied ever using Ozempic in her life, but that hasn’t stopped rumors claiming she has used it for weight loss in recent months.
“I just have to clarify: I’ve never taken Ozempic. I don’t know what Ozempic does to you other than what I saw it do to my mom,” she told People last May.
She nevertheless called it a “miracle” substance when in the right hands, saying: “If you need to lose some weight, who cares how you do it, as long as you’re doing it in a healthy way.”
The daughter of A-list parents Ozzy and Sharon Osbourne said she has taken different “peptides” and “vitamins” and has her own weight loss journey.
Kelly has previously said she lost 85 pounds after gastric bypass surgery in 2020 and also lost weight after becoming a mother to her son, Sidney, in 2022.
Christina Aguilera
The internet called Christina Aguilera a “genie on Ozempic,” claiming her appearance changed dramatically in recent years.
The singer, who has faced constant speculation about using Ozempic, has never directly addressed using any kind of GLP-1 medication. But she slammed the constant obsession over her weight as it changed over her decades-long career.
“When you’re a teenager, you have a very different body than when you’re in your 20s,” she told Glamour last August.
After her body started to “fill out,” people found it “unacceptable” that she was getting “thicker.”
“Then I had industry people: ‘They liked your body and how you were as a skinny teenager,’” she told the outlet.
Scott Disick
Boxes of Mounjaro, which is known for its weight loss effects, were found stacked in Scott Disick’s fridge on a past episode of The Kardashians.
Fans expressed concern over the past year after he looked noticeably thin and wondered whether it was because of some kind of GLP-1 medication.
A source later claimed that he gave up on weight loss medication because of his teenage son forcing him to take “accountability.”
“Mason was the main reason” Scott gave up on Mounjaro, the source told the Daily Mail.
“Having Mason move in with him full-time has been a complete game changer,” the source added.
Ariana Grande
Ariana Grande’s “skeletal” appearance has triggered health concerns among fans over the last year.
Many even questioned whether she was relying on the weight loss jabs for her slim, slender appearance. Her recent appearance on the Golden Globes red carpet was no exception to the guesswork about her appearance.
The Side to Side singer recently grew emotional when asked how she “copes” with the constant criticism about her appearance and beauty standards.
“I’ve been kind of doing this in front of the public,” she told a French journalist in December.
Describing herself as “a specimen in a petri dish” since the age of “16 or 17,” she said: “I have heard it all.”
Sharon Osbourne
Sharon Osbourne has not only admitted to taking Ozempic but also said she “went too far” with the medication.
The 72-year-old said it’s “not a sin” to use it and said she lost “three stone [42 pounds] in four months,” which she described as “too much.”
“I don’t know what it’s done to my metabolism, but I just can’t seem to put any [weight] on because I think I went too far,” she said in a podcast with Howie Mandel last year.
Last September, she said she weighed just seven stone and couldn’t put on weight.
“I’m through with the weight loss and all that cosmetic stuff,” she told The Guardian.
Kelly Clarkson
Kelly Clarkson’s dramatic weight loss has been the subject of immense speculation.
The singer spoke about losing “a lot” of weight during a conversation with Whoopi Goldberg on The Kelly Clarkson Show.
Whoopi, who has said she takes Mounjaro, spoke to Kelly about “that wonderful shot that works for folks who need some help.”
In response, the American Idol alum said she lost a significant amount of weight with the help of a medication, but she did not specify the details of her prescription.
“Everybody thinks it’s Ozempic. It’s not,” she said.
Katy Perry
Rumors about Katy Perry using Ozempic have been rampant in recent months.
“She’s definitely taking Ozempic!” a social media user claimed after her appearance at iHeartRadio Q102’s Jingle Ball in December.
Another agreed saying, “She is on Ozempic; you can not deny the Ozempic face.”
In the same month, she addressed her biceps, which were “going around the internet,” and said she actually hates working out.
“I love to dance, swim, and do things that don’t feel like working out,” she said.
The Fireworks singer herself poked fun at Ozempic rumors during her 40th birthday bash last October.
To her friends who joined her for the birthday celebration, she gave out goodie bags that included an empty mini-syringe emblazoned with the word OzempiKP.
Oprah
After years of being “exploited” by the tabloids for her weight, Oprah said she turned to an Ozempic-like medication to trim her waistline.
The talk show host, 71, hasn’t specified the brand of the GLP-1 medication she used but said it helped her almost hit her goal weight of 160 pounds (72 kg).
“Every week [I was] exploited by the tabloids; anytime any comedian wanted to make fun or make a joke about it, they would make a joke about it,” she said on her podcast last month.
“And I accepted it because I thought I deserved it,” she added.
Oprah previously said she didn’t want to take medication for weight loss because she felt it was “the easy way out.” But eventually, she released her “own shame about it” and consulted her doctor, who prescribed a weight loss medication.
“I now use it as I feel I need it, as a tool to manage not yo-yo-ing,” she told People in 2023.
Lizzo
Netizens have been relentless with their claims about Lizzo using Ozempic to aid her weight loss journey.
The Grammy winner addressed the rumor mill in an Instagram post in 2024.
“When you finally get Ozempic allegations after 5 months of weight training and calorie deficit,” read the text on a video clip included in the Instagram carousel.
“It’s like a reward,” she mouthed along with the clip’s audio.
Lizzo was roasted in an episode of South Park, which created a fictitious drug called “Lizzo” and branded it as a cheaper alternative to Ozempic.
“FDA-approved Lizzo makes you feel good about your weight, and it costs 90% less than Ozempic,” a voice-over said in the show.
The About Damn Time singer savagely clapped back at the long-running animated series with her Halloween costume last year.
She dressed herself up as an FDA-approved “diet suppressor” and shared a “LizzOzempic dump” of pictures for the occasion.
John Goodman
John Goodman’s dramatic weight loss transformation raised questions about how he managed to do so.
The onscreen star said he was his heaviest in 2011, weighing 400 lbs, but he managed to shed 200 lbs. However, it took him several years to get there.
“I wanted to do it slowly. Move, exercise,” he told ABC in 2017. I’m getting to the age where I can’t afford to sit still anymore.”
The Emmy winner revealed he cut out alcohol, began following a Mediterranean-style diet, and took at least 10,000 to 12,000 steps a day for his gradual 200-lb weight loss.